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Recommended Series | GelGreen Dye – A Safer and More Efficient Choice for Nucleic Acid Electrophoresis

2025/7/30 14:36:13 Browse volume(1)
Nucleic Acid Dye

Green DYE


"The moment an EtBr reagent bottle is opened, the lab air freezes - this isn't just protocol, it's deeply ingrained protective instinct."

This might be the late-night anxiety of countless molecular biologists. As nucleic acid staining links to long-term health risks, GelGreen arrives with its orange solution revolution:

· Water-soluble formulation directly compatible with gel systems, eliminating organic solvent exposure risks

· Blue light excitation produces high-contrast green fluorescence, precisely capturing trace nucleic acid signals

· Non-cytotoxic, non-mutagenic, and non-hazardous, redefining experimental safety boundaries

Now nucleic acid electrophoresis staining follows standard protection protocols, providing safer experimental support from DNA QC to RNA denaturing gel analysis.

I. Product Properties

Structure of GelGreen DYE

Chinese Name: GelGreen Dye

English Name: GelGreen DYE

CAS No.: NA

Molecular Formula: C56H80I2N8O52

Molecular Weight: 1199.12

Specification: 1 mg / 5 mg / 10 mg (Custom packaging available)

Appearance: Orange aqueous solution

Catalog No.: G10040028

GelGreen is a highly sensitive, non-toxic green fluorescent nucleic acid dye primarily used for staining dsDNA, ssDNA, and RNA in nucleic acid gel electrophoresis. It serves as an ideal replacement for EtBr and other traditional nucleic acid stains.


II. Application Scenarios

1. Agarose Gel Electrophoresis: For separating and visualizing DNA and RNA fragments in agarose gel electrophoresis.

2. Polyacrylamide Gel Electrophoresis: For separating and visualizing DNA and RNA fragments in polyacrylamide gel electrophoresis.

3. Nucleic Acid Electrophoresis: Replaces traditional ethidium bromide (EtBr) staining for DNA and RNA electrophoresis.


III. Core Advantages

1. High Sensitivity: GelGreen has ultra-high sensitivity, significantly outperforming common dyes like EtBr, SYBR Safe , etc., enabling detection of low-concentration nucleic acids.

2. Non-Toxic: Verified by multiple experiments, GelGreen is non-cytotoxic and can be disposed as regular waste at working concentrations, reducing lab waste disposal costs.

3. Strong Stability: Excellent thermal and hydrolytic stability prevents performance degradation from repeated freeze-thaw cycles.

4. Compatible with Blue & UV Light: GelGreen works with both UV and blue light imaging systems. Clear signals under blue light excitation avoid UV damage to personnel and DNA samples, enhancing experimental safety and result reliability.


IV. Product Principle

GelGreen is a ready-to-use water-soluble fluorescent probe that emits low-background green light under 488 nm excitation, ideal for efficient nucleic acid detection. Its unique molecular design ensures excellent thermal and hydrolytic stability while avoiding cell membrane penetration and bioaccumulation issues. Safely usable for live-cell nucleic acid labeling and high-throughput electrophoresis analysis without lysis or washing steps, significantly improving experimental efficiency and safety.



Extended Services

We simultaneously provide various nucleic acid dyes and related materials. For more customized solutions or technical consultations, please call +86 13302967066!


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Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd.

Established in 2015, we are a high-tech enterprise specializing in microbial detection, gene sequencing and in vitro molecular diagnostics, focusing on R&D, production, and sales of biochemical reagent raw materials. Committed to providing high-quality biochemical reagent raw materials and professional custom synthesis services, our product range covers over ten categories with nearly a thousand innovative products. Upholding the core philosophy of "Customer First, Integrity and Professionalism", we serve with dedication to meet diverse customer needs in research and testing.

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