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In Stock Series | NGS Nucleotide Building Block Iodo-dA: The “Molecular Foundation” Redefining Sequencing Stability
2025/11/20 14:21:077-Deaza-7-iodo-2′-deoxyadenosine (CAS: 166247-63-8) is a modified nucleoside specifically optimized for next-generation sequencing (NGS). It enhances sequencing performance in high-GC regions and enables nucleic acid functionalization, probe design, and conjugation to payloads such as ApDC (antibody–drug conjugates). GeneSeqTools offers this key reagent in kilogram-scale stock with flexible packaging options to meet both research and industrial-scale demands.
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In Stock Series | From “Analysis” to “Construction”: How DBCO-dT-CE Phosphoramidite Empowers Nucleic Acids with Functional Versatility
2025/11/11 15:18:30DBCO-dT-CE phosphoramidite is a ready-to-use functional monomer that enables precise incorporation of a "click chemistry" handle during solid-phase DNA synthesis. Through highly efficient, copper-free cycloaddition reactions, it seamlessly conjugates with a wide range of azide-modified molecules—facilitating applications such as targeted delivery of nucleic acid therapeutics and multifunctional labeling of diagnostic probes. This versatile building block accelerates innovation in nucleic acid drug development, molecular diagnostics, and nanotechnology research.
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In Stock Series | 8-oxo-dG-CE Phosphoramidite (143060-53-1): A Molecular Tool for Precise Detection of DNA Oxidative Damage
2025/11/4 14:59:128-oxo-dG-CE phosphoramidite (CAS: 143060-53-1) is a core reagent for studying DNA oxidative damage. Through solid-phase chemical synthesis, it enables site-specific incorporation of the 8-oxo-2'-deoxyguanosine (8-oxo-dG) lesion into oligonucleotides, facilitating research on mutagenesis mechanisms and the functional analysis of DNA repair enzymes. GeneSeqTools offers this high-purity phosphoramidite in multiple packaging sizes, as well as custom oligonucleotide synthesis services with site-specific modifications to support advanced genomic and biochemical research.
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In Stock | 3′-O-Azidomethyl-dNTP Derivative Nucleoside Triphosphates: Reversible Termination for Accurate Sequencing
2025/10/28 14:05:083′-O-Azidomethyl-dNTPs enable reversible termination of DNA chain elongation through chemical modification at the 3′-hydroxyl group, supporting high-throughput sequencing and base-by-base detection. Featuring a compact modifier structure and strong compatibility with DNA polymerases, these dNTPs allow clean deprotection with no residual modifications in the DNA backbone. The product series includes all five canonical bases (A, C, G, T, and U), providing researchers with reliable core reagents for next-generation sequencing and related applications. GeneSeqTools is committed to empowering scientific discovery with high-purity, performance-verified building blocks.
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In Stock | Lighting Up the RNA World with "Click" Chemistry — 5-Ethynyl-UTP: A New Solution for Nascent RNA Labeling
2025/10/22 17:13:065-Ethynyl-UTP (5-Ethynyluridine 5ʹ-triphosphate) is a chemically modified nucleoside triphosphate capable of direct incorporation into RNA. With high sensitivity, excellent specificity, and superior biocompatibility, it has become an ideal choice for metabolic labeling of nascent RNA. Through click chemistry, 5-Ethynyl-UTP enables visualization, quantification, and sequencing of newly synthesized RNA, providing powerful support for studies on transcriptional activity and RNA turnover dynamics.
